I have found you shouldn't go below 140,000 pf with a 45cap, at least out of a glock 21(even with light recoil springs). Another load was 200gr Montana Gold FP with about 4.2 grains of Clays, but kept the OAL, short at about 1.190. Yes, you may get to a 130000 PF with 45 acp, but when the weak hand only cause malfunctions, you will see that striving for 130000 wasn't such a good idea. Been there, done that!
Your 5.25 barrel is about .75 in. longer than the barrel I used, so you could drop the charge a bit for that.