Yes, that is usually the situation. When all chambers have late timing, the hand is probably too thin. A wider hand will make it lock up sooner. When one or two chambers are late and the rest are OK, it is usually the ratchets related to those chambers that are different from the others. In that case, you can peen the offending ones to make them wider towards the hand, or get a new extractor (with new ratchets on it).
Working on the ratchets is the most fiddly part of revolver work. It's easy to mess them up so they don't work at all. It's best not to mess with them if at all possible unless you are already experienced at it. Experience is what you get right after you need it. Sometimes you can bend the hand inward (towards the center pin of the cylinder) slightly to advance the timing.