Well I guess the real question is what do you mean by best? You looking for max performance? Low flash? Overall accuracy?
What are you gonna be shooting with this load? Paper? Steel? ect,
tonythetiger is right there is no one size fits all. What works in your gun might not work in others. If you give some more info that would help out a lot, and don't say all of the above. You are gonna have to make sacrifices in some categories to improve others, there is no such thing as a perfect load.