Because of the rules and scoring each caliber has its own advantages/disadvantages in each division. For instance 9mm is the dominant caliber in Production because all calibers are scored Minor regardless of PF, but the minimum caliber for Limited Major is .40, so most Limited shooters shoot .40 over .45 because of the capacity limitations of .45s. In L10 the capacity issue goes away and so does the disadvantage of the .45, same in Single Stack.