The only thing really different is your reloads. For that you just have to figure out what works for you.
I jusy doodled around with it a little.
When you go to do your reload rotate your hands around as one so your right thumb comes over to hit the release. Your left hand is then in perfect position for your figers to push though the cylinder window to open the the cylinder. At this point you are reloading just like most everybody else. Your gun is in your left hand you grab a moon clip with you left hand. Find the video of Jerry doing his 6 reload and 6 more and watch how he does it.
Some folks do it differently, Patrick does I know.
Now you palm the whole gun in you right hand and let your left hand slide back to the grip and bring you right hand back to your regular support position.
Yes it will take some practice. EVERYTHING with revolvers takes more practice and more work.
BUT BUT BUT, if you do the work and learn to shoot a revolver well it will make you a better shooter with an auto loader.
Good luck and don't give up without trying.