i try to keep mine sorted . for me it make loading go a lot smoother on the dillon 650.
to me i can feel the difference between the resizing of some different brand brass and it just throws your pace off when one goes super easy or really hard. have had a brand also not flare the case mount as much as another so when your loading if you may smash some cases if not holding bullets all the way up into the die.
i use case lube as well so that isnt the problem of feeling difference in sizing.
to me it not a huge deal just do a little every once and a while grab a bucket of clean brass and a towel and just start making a pile between win ,rp ,federal , starline everything else goes into a bucket to be sold as range brass