I have set up multiple 650's for first time loaders and have one myself, and have a couple of suggestions to anyone new to reloading and considering a Dillon for a first press. To those familiar with flying, I think buying a Dillon 650 for your first endeavor into reloading is kind of the equivalent of getting a Mooney for your first airplane.
1. If you aren't REALLY mechanically inclined and/or have a readily available source of assistance from someone with progressive loading experience (preferably with Dillon) to get you through the speed bumps, seriously consider getting a Redding T7 (search on youtube if you want to see one in action; evidently I can't put links in my post as a new member) or equivalent first or with your Dillon. The turret press is highly affordable and allows you to directly see/engage the same conceptual circular assembly line process flow that progressive presses use only with far fewer variables going on, and while allowing easy modifications at any point.
2. If you fit the above but are the mechanical/engineering wiz (or have access to the aforementioned mentor) and want the Dillon as your first press, consider getting a T7, or similar turret press along with or as a compliment to your Dillon anyway. We buy the high speed, low drag Dillon machines for convenience, but they specialized to be convenient for mass replication of a load formula..not for developing it. That is where, I have found, turret presses seem to offer superior convenience for load development and low production run calibers. Just a thought...
-Raider