Depends on what barrel lenght you decide on.
I just had an open minor gun built using that single port comp. Ended up using a KKM 5" oal threaded bull barrel, dawson tooless full lenght guide rod, reverse plug.
I believe the gunsmith had to cut roughly .400" off the front of the slide and the had to extend the bottom cuts on the comp to line up with the full dustcover frame.
If I recall correctly I think its fit slide, frame, barrel, then install comp onto barrel, measure how much needs cut from front of slide.
The sight block i think would be similar in fitting.
I think the nemesis is a 5.4" barrel (somone please correct me if i'm wrong) so might not need to nip the end of slide for sight block fitment.
But i do know the erebus is slightly shorter then 5" oal barrel as putting my gun next to an erebus there is roughly 3/8" difference in lenght.
Again, this is all dependant on the barrel you decide to go with.
Dunno if this helped or not, just going off memory of working with the smith who built my guns and having handled my friends erebus and nemesis. I'm very happy with the finished product and the 5" barrel with single comp shooting minor is really soft shooting and tons of fun.