Chuck D, I also have pretty wide hands and use a grip as high as you can when shooting a glock, both thumb nails are as high as the top of the slide. When I first moved over to shooting a Glock I was getting pretty torn up. The first week I started shooting the glock we went on a training trip to Blackwater. We shot around 800 rounds a day for 5 days. It was so bad that I had blood and skin all the way up under the slide as far forward as the locking block. Pretty nasty. Anyhow.....I didn't so much change my grip as I did the way I come into the gun. Meaning, when you draw the gun, come up the backstrap instead of down onto it. It's not as big of a change as you might think in your draw stroke. A few hundred draws and you should have it down. Good luck
Jason