Interesting theory. I'll adjust the crimp and see if it helps. Do you have a crimp measurement you can share?
I don't measure stuff like that. I just do it by feel. On a progressive machine, it's pretty easy to lose track of that feel. I had very consistent results with both clays and n320 last year when I was loading on a single-stage, however, so that's what got me thinking. I don't believe it's a concern with 9mm or 40 because those rounds operate at much higher pressures, but 45 is a pretty low-pressure round, so it seems plausible that lack of crimp could lead to inconsistent combustion. I seriously had like no crimp tho.
I'll check tonight or tomorrow. I'll measure and also pull a bullet to see if has any indication of a crimp.