I run exactly the same load (4.1) over 125 Bear Creek moly in two G 34s. I use mixed stamp and get about 30 FPS variation. Between normal powder dispensing variability +/- .1 gr and mixed stamps I think thats pretty good. Doesn't affect accuracy to my ability to test. Maybe off a mechanical rest but not me off a rest at 25 yards.
I have shot a thousand rounds in a day without cleaning, each gun, two shooters during a class. Did not see enough lead/moly buildup to get worried. 5 minutes with a lead cleaner in the bore and a few passes, patches come out clean.