Several years ago, I carried a fullsize 92FS for 3 years straight - every day. It's doable, but I wouldn't say it was comfortable. It never was
Later, I used the same Comptac holster and carried a 92FS compact for a while. There is not much weight difference between the two. Size wise, it's not much bigger than many other carry guns... (the compact 92FS or 92X compact). BUt, it IS heavier than many of the polymer guns.
However, lots of guys at the Beretta Forum carry fullsize 92's.
I am a HUGE Beretta fanatic. I have owned 28 different 92 variants over 25+ years, and 39 Berettas in total. But, I'll stick to lighter, polymer guns now...