I have tried to like the P365 in it's different configurations (365, 365X. 365XL, 365 Macro, etc.). There are two issues that have been deal breakers for me:
1. The pistol is actually too narrow for me. I have very large (size 12 - X Large gloves) and it just seems the pistol squirms around too much
2. The trigger. In my opinion, the 320 trigger is vastly superior to the 365 trigger.
I prefer a 320 X-Compact or X-Carry for EDC, and can shoot them much better than I can a 365.
But it all comes down to what works best for you, based on your hand size, experience, and personal preference.